🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧪 Experimental Design

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Trial Search

Current Search Criteria:

Intervention: Ketamine infusion

Found 758 matching trials

Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe Depression

This project employs a prospective, randomized, controlled, blinded, dual-c...

Status

Not Yet Recruiting

Location

Multiple Locations

Start Date

2026-01-18

Trial ID

NCT07374211

Treatments Being Tested

Esketamine 0.3mg/kg normal saline

Ketofol Versus Propofol for Sedation in Cholangiopancreatography for ASA III and ASA IV Patients.

This study is a double blind randomized controlled trial. The investigators...

Status

Completed

Location

Multiple Locations

Start Date

2016-10-01

Trial ID

NCT05473949

Treatments Being Tested

Profofol for Sedation in Cholangiopancreatography for ASA III and ASA IV Patients Ketofol for Sedation in Cholangiopancreatography for ASA III and ASA IV Patients

Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.

PHASE4

The purpose of this study is to determine if there is a difference in patie...

Status

Completed

Location

Hospital for Special Surgery, New York

Start Date

2017-01

Trial ID

NCT02996591

Treatments Being Tested

25 mL of 0.25% bupivacaine plus 2 mg preservative-free (PF) dexamethasone / 30 ml for popliteal nerve block 10 mL of 0.25% bupivacaine plus 2 mg preservative-free (PF) dexamethasone / 30 ml for adductor canal nerve block Midazolam, 2-5 mg IV + Glycopyrrolate, 0.1 mg IV + Ketamine, 10-20 mg + propofol as needed 45-60 mg of 1.5% mepivacaine for spinal anesthesia LMA insertion + titrated propofol infusion + sevoflurane + ketamine 10 mg/hr for general anesthesia

Effects Of PF-02545920 On Ketamine-Induced Abnormal Prefrontal Brain Response To Associative Learning In Healthy Subjects

PHASE1

To evaluate whether PF-02545920 reduces the effects of ketamine on brain ac...

Status

Terminated

Location

Pfizer Investigational Site

Start Date

2011-04

Trial ID

NCT01244880

Treatments Being Tested

Saline PF-02545920 Ketamine PF-02545920 Saline Placebo Ketamine Placebo

Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery

This study is a randomized, double-blinded, controlled design. In this stud...

Status

Unknown

Location

Tianjin Nankai Hospital

Start Date

2021-05-10

Trial ID

NCT04873479

Treatments Being Tested

S-ketamine saline

Double-Blind Trial of Ketamine Therapy Plus or Minus Naltrexone in Treatment Resistant Depression (TRD)

PHASE1

The primary objective is to determine if the opioid properties of ketamine ...

Status

Completed

Location

Stanford University

Start Date

2016-09

Trial ID

NCT02911597

Treatments Being Tested

Naltrexone

Multimodal Analgesia in Cardiac Surgery (Pilot Study)

PHASE4

The investigators objective is to assess the effectiveness of an opioid spa...

Status

Terminated

Location

Virginia Commonwealth University

Start Date

2016-07-11

Trial ID

NCT02734940

Treatments Being Tested

Lidocaine Unrestricted Fentanyl Ketamine Precedex Duramorph

Low-dose S-Ketamine and Postpartum Depression in Parturients With Prenatal Depression

Prenatal depression is an important risk factor of postpartum depression. L...

Status

Completed

Location

Peking University First Hospital

Start Date

2020-06-19

Trial ID

NCT03927378

Treatments Being Tested

S-ketamine Placebo

Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe Depression

A Dual-Center, Randomized, Controlled, Blinded, Prospective Study on the Ef...

Status

Not Yet Recruiting

Location

Multiple Locations

Start Date

2026-01-18

Trial ID

NCT07374198

Treatments Being Tested

Esketamine 0.3mg/kg normal saline

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

PHASE2

Background: Major depressive disorder (MDD) is a serious mental illness th...

Status

Recruiting

Location

National Institutes of Health Clinical Center

Start Date

2024-11-06

Trial ID

NCT06511908

Treatments Being Tested

(2R,6R)-hydroxynorketamine (0.25 to 2.0 mg/kg)Placebo

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